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A patient is suffering from ADA deficiency. Can he be cured? H
Biology Exemplar
Biology Exemplar

Class 12

NCERT Exemplar

Publisher:
NCERT
Subject:
Biology
1

Chapter 1: Reproduction in Organisms

48 questions

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2

Chapter 2: Sexual Reproduction in Flowering Plants

52 questions

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3

Chapter 3: Human Reproduction

48 questions

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4

Chapter 4: Reproductive Health

37 questions

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5

Chapter 5: Principles of Inheritance and Variation

52 questions

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6

Chapter 6: Molecular Basis of Inheritance

71 questions

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7

Chapter 7: Evolution

52 questions

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8

Chapter 8: Human Health and Disease

70 questions

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9

Chapter 9: Strategies for Enhancement in Food Production

77 questions

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10

Chapter 10: Microbes in Human Welfare

59 questions

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11

Chapter 11: Biotechnology: Principles and Processes

48 questions

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12

Chapter 12: Biotechnology and its Applications

52 questions

Q1
Transgenic animals are the animals in which a foreign gene is expressed. Such animals can be used to study the fundamental biological process, phenomenon as well as for producing products useful for mankind. Give one example for each type.
Q2
A patient is suffering from ADA deficiency. Can he be cured? How?
Q3
Highlight five areas where biotechnology has influenced our lives.
View all question
13

Chapter 13: Organisms and Populations

70 questions

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14

Chapter 14: Ecosystem

68 questions

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15

Chapter 15: Biodiversity and Conservation

61 questions

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16

Chapter 16: Environmental Issues

52 questions

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A patient is suffering from ADA deficiency. Can he be cured? How?

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Biology Exemplar (NCERT Exemplar)

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Text SolutionText solutionverified iconVerified

ADA enzyme is crucial for the immune system to function. Deletion of the gene for adenosine deaminase results into ADA deficiency.
In some children, ADA deficiency can be cured by bone-marrow transplantation, while in others it can be treated by enzyme replacement therapy, in which functional ADA is given to the patient by injection. But the problem with both of these approaches is that they are not completely curative.
It may recurrent in nature as in the process of gene therapy, lymphocytes used are found not to be immortal in nature and the patient requires a periodic infusion of such genetically engineered lymphocytes.
For permanent cure, gene isolated from the bone-marrow cells producing ADA is introduced into cells at early embryonic stages.
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Question Text
A patient is suffering from ADA deficiency. Can he be cured? How?
TopicBiotechnology and its Applications
SubjectBiology
ClassClass 12
Answer TypeText solution:1
Upvotes131