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Please answer part A and B, thank you. 9. This diagram illustrates the evolution of the human globin gene family from an ancestral gene, which was discussed in lecture on Wed. Oct. 11. cxp-globin ancestral gene a-globin B-0lout T J Eglobin 2-globin 1-globin -globin -globin -globin Questions on page next Three genes on chromosome 16 in humans Five genes on chromosome 11 a. Which of the other 5 genes on the bottom row illustrating the globin gene family in modern humans (3 on chc 16 + 2 on chc 11) are paralogs of fglobin? Include a one-sentence rationale for your answer that demonstrates your understanding of the definition of a paralog. b. Hemoglobin is a tetramer of two f-globin subunits and two globin subunits. Why do mutations disrupting the globin gene cause red blood cell disorders while -globin mutations don't?
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Question Text | Please answer part A and B, thank you.
9. This diagram illustrates the evolution of the human globin gene family from an ancestral gene, which was discussed in lecture on Wed. Oct. 11.
cxp-globin ancestral gene
a-globin
B-0lout
T
J
Eglobin 2-globin 1-globin
-globin -globin -globin
Questions on page
next
Three genes on chromosome 16 in humans
Five genes on chromosome 11
a. Which of the other 5 genes on the bottom row illustrating the globin gene family in modern humans (3 on chc 16 + 2 on chc 11) are paralogs of fglobin? Include a one-sentence rationale for your answer that demonstrates your understanding of the definition of a paralog.
b. Hemoglobin is a tetramer of two f-globin subunits and two globin subunits. Why do mutations disrupting the globin gene cause red blood cell disorders while -globin mutations don't? |
Topic | All topics |
Subject | Biology |
Class | Class 11 |