Many pharmaceutical drugs currently in use bind to a specific "drug target" protein, and in that way alter the function of this target protein. Applications of this approach to [ Select ] ["", "", "tumor suppressor genes", "immuno-oncology"] for the treatment of cancer patients is [ Select ] ["straightforward", "complicated"] because the protein involved is [ Select ] ["“undruggable”", "absent or non-functional"] in cancer cells, removing the possibility of modulating their function [ Select ] ["by drug binding", "checkpoint inhibition"].

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