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Inhibition of Nucleotide Synthesis by Azaserine The diazo compound -L-serine, known also as azaserine (see Fig. ), is a powerful inhibitor of glutamine amidotransferases. If growing cells are treated with azaserine, what intermediates of nucleotide biosynthesis will accumulate? Explain.
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Question Text | Inhibition of Nucleotide Synthesis by Azaserine The diazo compound -L-serine, known also as azaserine (see Fig. ), is a powerful inhibitor of glutamine amidotransferases. If growing cells are treated with azaserine, what intermediates of nucleotide biosynthesis will accumulate? Explain. |
Topic | All topics |
Subject | Biology |
Class | Class 11 |