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However, this region plays a significant role in the maintenance of ifigh osmolarity of medullary interstitial fluid, The descending limb of loop of Henle is permeable to water but almost impermeable to electrolytes. hilis concentrates the filtrate as it moves down. The ascending impermeable to water but allows transport of electrolytes actively or passively. Therefore, as the concentrated filtrate pass upward, it gets diluted due to the passage of electrolytes to the medullary fluid. Distal Convoluted Tubule (DCT): Conditional reabsorption of Nat and water takes place in this segment. DCT is also capable of reabsorption of ${\mathrm{HCO}}_3^{-}$and selective secretion of hydrogen and potassium ions and ${\mathrm{NH}}_3$ to maintain the $\mathrm{pH}$ and sodium-potassium balance in blood.

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Updated on: Apr 25, 2023