Which of the following option(s) is/are correct regarding catalytic activity?

Conversion of proteins into amino acids by hydrolysis in intestine is catalysed by enzyme pancreatic trypsin.

In case of fever, the activity of bio-chemical catalyst gets adversely affected.

In heterogeneous catalysis, the reactants must get adsorbed reasonably strong on the catalyst surface but not so strongly that desorption of product becomes impossible.

In the decomposition of methyl urea, enzyme urease acts as a catalyst.